7-Aminocephalosporanic acid → HCID 70530713, compound

HRID 648421Notes

Reaction equation

HRID 648421 reaction equation
CC(O[CH2:5][C:6]1[CH2:15][S:14][C@@H:9]2[C@H:10]([NH2:13])[C:11](=[O:12])[N:8]2[C:7]=1[C:16]([OH:18])=[O:17])=O.[CH3:19][O:20][C:21]([CH2:23][N:24]1[C:28]([SH:29])=[N:27][N:26]=[N:25]1)=[O:22]>>[NH2:13][CH:10]1[C:11](=[O:12])[N:8]2[C:7]([C:16]([OH:18])=[O:17])=[C:6]([CH2:5][S:29][C:28]3[N:24]([CH2:23][C:21]([O:20][CH3:19])=[O:22])[N:25]=[N:26][N:27]=3)[CH2:15][S:14][C@H:9]12

Participants

3

Reactant 2

HCID 4413287-Aminocephalosporanic acidHCID 178501553HCID 178501553, compound

Product 1

HCID 70530713HCID 70530713, compound

Procedure

7-Aminocephalosporanic acid was reacted with 1-methoxycarbonylmethyl-1H-tetrazole-5-thiol in a conventional manner to give 7-amino-3-(1-methoxycarbonylmethyl-1H-tetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid.

Sources & evidence

ORD record
ord-b120fab825af48548c17e0a4559a0318
Source dataset
uspto-grants-1983_10
Patent number
US04411898

Reaction notes

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