Trifluoroacetic acid → HCID 131715481, compound
Reaction equation
C(OC([NH:8][C:9]1[S:10][CH:11]=[C:12](/[C:14](=[CH:42]/[S:43]([CH3:46])(=[O:45])=[O:44])/[C:15]([CH:17]2[C:40](=[O:41])[N:19]3[C:20]([C:33]([O:35]C(C)(C)C)=[O:34])=[C:21]([CH2:25][S:26][C:27]4[N:31]([CH3:32])[N:30]=[N:29][N:28]=4)[CH:22]([NH2:24])[S:23][C@H:18]23)=[O:16])[N:13]=1)=O)(C)(C)C.[F:47][C:48]([F:53])([F:52])[C:49]([OH:51])=[O:50]>>[F:47][C:48]([F:53])([F:52])[C:49]([OH:51])=[O:50].[NH2:8][C:9]1[S:10][CH:11]=[C:12](/[C:14](=[CH:42]/[S:43]([CH3:46])(=[O:45])=[O:44])/[C:15]([CH:17]2[C:40](=[O:41])[N:19]3[C:20]([C:33]([OH:35])=[O:34])=[C:21]([CH2:25][S:26][C:27]4[N:31]([CH3:32])[N:30]=[N:29][N:28]=4)[CH:22]([NH2:24])[S:23][C@H:18]23)=[O:16])[N:13]=1Participants
3
Procedure
When the product prepared in Example 6 is treated with trifluoroacetic acid as described in Example 5, the title compound is obtained.
Sources & evidence
- ORD record
- ord-909f97ba22224a3e80fdcf231ca59d42
- Source dataset
- uspto-grants-1988_04
- Patent number
- US04735938
Reaction notes
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