Hydrochloric Acid → HCID 20145067, compound

HRID 648605Notes

Reaction equation

HRID 648605 reaction equation
[CH3:1][NH:2][C:3]1[S:4][C:5]([C:9]2[S:13][C:12]([NH:14][CH3:15])=[N:11][C:10]=2[CH3:16])=[C:6]([CH3:8])[N:7]=1.[ClH:17]>C(O)C>[ClH:17].[ClH:17].[CH3:1][NH:2][C:3]1[S:4][C:5]([C:9]2[S:13][C:12]([NH:14][CH3:15])=[N:11][C:10]=2[CH3:16])=[C:6]([CH3:8])[N:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15505523HCID 15505523, compound

Product 1

HCID 20145067HCID 20145067, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a suspension of 2,2'-dimethylamino-4,4'-dimethyl-5,5'-bithiazole (1.9 g) in ethanol (100 ml) was added conc. hydrochloric acid (2 ml) and the resulting solution was evaporated in vacuo. The residue was dissolved in ethanol (100 ml) and the solution was concentrated in vacuo. The resulting precipitate was collected by filtration and washed with diethyl ether to give 2,2'-dimethylamino-4,4'-dimethyl-5,5'-bithiazole dihydrochloride (1.86 g). mp 277° C. (dec.).

Workup

  1. customthe resulting solution was evaporated in vacuo
  2. dissolutionThe residue was dissolved in ethanol (100 ml)
  3. concentrationthe solution was concentrated in vacuo
  4. filtrationThe resulting precipitate was collected by filtration
  5. washwashed with diethyl ether

Sources & evidence

ORD record
ord-3618fec4a10c451a88b94401ac0d20d7
Source dataset
uspto-grants-1988_04
Patent number
US04735957

Reaction notes

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