HCID 20145121, compound → HCID 20145110, compound

HRID 648632Notes

Reaction equation

HRID 648632 reaction equation
[N:1]1([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[C:13]([CH:15]([C:25]([NH2:27])=[O:26])[C:16]2[CH:24]=[CH:23][C:19]([C:20]([OH:22])=[O:21])=[CH:18][CH:17]=2)=[CH2:14])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[H][H]>C(O)C.[Pd]>[N:1]1([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH:13]([CH:15]([C:25]([NH2:27])=[O:26])[C:16]2[CH:17]=[CH:18][C:19]([C:20]([OH:22])=[O:21])=[CH:23][CH:24]=2)[CH3:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

5

Reactant 2

HCID 20145121HCID 20145121, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 20145110HCID 20145110, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

One hundred milligrams (0.2744 m mol) of 4-[(1-(2-piperidino-phenyl)-ethenyl)-aminocarbonylmethyl]-benzoic acid in 5 ml of absolute ethanol were hydrogenated in the presence of 50 mg of palladium/charcoal (10%) at 20° C. and at a hydrogen pressure of 1 bar under shaking. After 1.5 hours the catalyst was filtered off, and the filtrate was evaporated in vacuo.

Workup

  1. filtrationAfter 1.5 hours the catalyst was filtered off
  2. customthe filtrate was evaporated in vacuo

Sources & evidence

ORD record
ord-3e08ba48da064ac7b147909a50831d62
Source dataset
uspto-grants-1988_04
Patent number
US04735959

Reaction notes

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