Acetic Anhydride → HCID 20145283, compound

HRID 648642Notes

Reaction equation

[OH:1][C:2]1[CH:3]=[CH:4][C:5]([N:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[C:6]([CH:8]([CH:10]([C:20]([NH2:22])=[O:21])[C:11]2[CH:19]=[CH:18][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=2)[CH3:9])[CH:7]=1.[C:29](OC(=O)C)(=[O:31])[CH3:30]>>[C:29]([O:1][C:2]1[CH:3]=[CH:4][C:5]([N:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[C:6]([CH:8]([CH:10]([C:20]([NH2:22])=[O:21])[C:11]2[CH:19]=[CH:18][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=2)[CH3:9])[CH:7]=1)(=[O:31])[CH3:30]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 20145113HCID 20145113, compound

Product 1

HCID 20145283HCID 20145283, compound

Procedure

An amount of 0.35 gm (0.915 m mol) of 4-[(1-(5-hydroxy-2-piperidinophenyl)-ethyl)-aminocarbonylmethyl]-benzoic acid was heated together with 0.103 ml (1.098 m mol) of acetic anhydride on a steam bath, and after standing for four days at 20° C., the reaction mixture was recrystallized from methanol.

Workup

customthe reaction mixture was recrystallized from methanol

Sources & evidence

ORD record: ord-bb4610f24e3d48d591d00921f6d1e797
Source dataset: uspto-grants-1988_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04735959

Reaction notes

Loading…