HCID 13281044, compound → HCID 13281105, compound

Participants

Reaction Steps

An amount of 1.1 gm (2 m mol) of 4-{N-[α-(4-benzyloxyphenyl)-2-piperidino-benzyl]-aminocarbonylmethyl}-benzoic acid was suspended in 200 ml of ethanol and catalytically debenzylated at 50° C., under a hydrogen pressure of 5 bar, in the presence of 0.4 gm of 10% palladium/charcoal. Then, the catalyst was filtered off, and the filtrate was concentrated by evaporation and recrystallized from acetonitrile.

Provenance & Evidence