HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 64868Generated: October 25, 2026
p-Anisoyl chloride → 4-(4-Methoxybenzoyl)-piperazin-1-yl-acetic acid pyrrolidide hydrochloride
https://huagongshe.com/reaction/64868
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | 1-((Pyrrolidine-1-carbonyl)methyl)piperazine | HCID 100614 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(4-Methoxybenzoyl)-piperazin-1-yl-acetic acid pyrrolidide hydrochloride | HCID 13371229 | — |
Reaction Steps
9.4 g of piperazin-1-yl-acetic acid pyrrolidide are dissolved in 10 ml of methylene chloride. A solution of 8.75 g of anisic acid chloride in 10 ml of methylene chloride is added dropwise at 0°. After the mixture had been stirred at 25° C. for 60 minutes, the crystals are filtered off with suction and dried in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04610984 |
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| Source dataset | uspto-grants-1986_09 |
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| ORD ID | ord-4b04545c2c6a4b479b8c744174660109 |
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| Source note | uspto-grants-1986_09 |
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