反应详情

Methyl 5-bromo-2-naphthoate (6.0 g) in benzene (100 ml) was cooled at 7° and a 70% solution of Vitride (sodium dihydro bis-2-methoxyethoxy aluminate) (10 ml) in benzene (20 ml)) was added dropwise with stirring. The solution was stirred for 4 hours at this temperature and decomposed with water and dilute hydrochloric acid. The benzene solution was separated and washed successively with dilute acid, saturated sodium bicarbonate solution and saturated sodium chloride solution, dried over sodium sulphate and evaporated to give a solid (4.8 g), m.p. 76°-77°.

1. stirringThe solution was stirred for 4 hours at this temperature
2. customThe benzene solution was separated
3. washwashed successively
4. additionwith dilute acid, saturated sodium bicarbonate solution and saturated sodium chloride solution
5. dry with materialdried over sodium sulphate
6. customevaporated