Hydrochloric Acid → HCID 20144340, compound

HRID 648950Notes

Reaction equation

HRID 648950 reaction equation
[CH2:1]([N:3]1[CH2:8][CH2:7][C:6]([C:10]2[CH:18]=[CH:17][CH:16]=[C:15]3[C:11]=2[CH:12]=[CH:13][NH:14]3)(O)[CH2:5][CH2:4]1)[CH3:2].Cl>C(O)C>[CH2:1]([N:3]1[CH2:4][CH:5]=[C:6]([C:10]2[CH:18]=[CH:17][CH:16]=[C:15]3[C:11]=2[CH:12]=[CH:13][NH:14]3)[CH2:7][CH2:8]1)[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 20144361HCID 20144361, compound

Product 1

HCID 20144340HCID 20144340, compoundYield 69.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using the procedure of Example 17, 2 g of the product of Example 19, 34 ml of ethanol and 66 ml of N hydrochloric acid were reacted to obtain 1.28 g of 4-(1-ethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole melting at 151° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-c62962d9f5014f1f9e6ba5d7f5855e34
Source dataset
uspto-grants-1988_04
Patent number
US04737505

Reaction notes

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