反应详情

10 g Isopropenylacetylene are taken up in abs. tetrahydrofuran and under an inert gas 94.5 ml of 1.6M solution of n-butyllithium in hexane added dropwise at -20°. The mixture is then cooled to -78° and 8.5 g of acrolein added dropwise. The reaction mixture is warmed to room temperature, poured into saturated aqueous NH4Cl and repeatedly extracted with ether. The organic phase is washed, dried and concentrated in vacuum. An oil is obtained.

1. temperatureThe mixture is then cooled to -78°
2. extractionrepeatedly extracted with ether
3. washThe organic phase is washed
4. customdried
5. concentrationconcentrated in vacuum
6. customAn oil is obtained