反应详情

温度

60 °C

The crude bis-(2,6-dichlorobenzoyl)-2,5-dimethylphenylphosphine (50 grams) is dissolved in 1 liter acetonitrile, mixed with 150 ml of 30% hydrogen peroxide, and heated for one hour at 60° C. The formation of the phosphine oxide is accompanied by deepening of the color, and it precipitates in crystalline form, after the addition of water and cooling. Recrystallization from acetonitrile/water yields 37 grams of the captioned compound (74% of theoretical yield in 2 steps)

1. customprecipitates in crystalline form
2. additionafter the addition of water
3. temperaturecooling
4. customRecrystallization from acetonitrile/water