Triethylamine → 3,3,3-Trifluoro-2-(trifluoromethyl)-1-propene

Temperature

60 °C

In a four necked 100 ml flask equipped with a condenser, a dropping funnel and a thermometer, triethylamine (20.0 g, 198 mmol) was charged and warmed to 60° C. Monochloromethyl 2-trifluoromethyl-3,3,3-trifluoropropanoate (4.88 g, 20 mmol) was dropwise added thereto while stirring. The reaction was continued at the same temperature as above for 2.5 hours while stirring. The gas evolved from a top of the condenser was washed with an alkaline solution, dried with alumina and cooled. The resultant liquid was distilled to give 2-trifluoromethyl-3,3,3-trifluoropropene (2.36 g). Yield, 72 %.

1. customIn a four necked 100 ml flask equipped with a condenser, a dropping funnel
2. customwas continued at the same temperature as above for 2.5 hours
3. stirringwhile stirring
4. washwas washed with an alkaline solution
5. customdried with alumina
6. temperaturecooled
7. distillationThe resultant liquid was distilled

ORD record

ord-aff203f37a08462aaa4f586ce4576715

Source dataset

uspto-grants-1988_04

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04739123