HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2-Cyano-2-phenylacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 10866842 | HCID 10866842 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2-Cyano-2-phenylacetamide | HCID 223587 | 75% |
Reaction Steps
A 10% solution of methyl 2-cyano-2-phenylacetate in benzene is saturated with ammonia under ice cooling. The reaction mixture is allowed to stand at room temperature for 2 hours, and then the product is filtered off. 2-Cyano-2-phenylacetic acid amide is obtained with a yield of 75%; m.p.: 148.5°-150° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04740228 |
| Source dataset | uspto-grants-1988_04 |
| ORD ID | ord-fbe203fd70f64ea5ae552f9b04e0a270 |
| Source note | uspto-grants-1988_04 |