Pyridine → HCID 14076561, compound

Participants

Reaction Steps

11 g of 2-cyano-2-ethyl-2-phenylacetyl bromide are added dropwise under cooling, at 20° to 30° C., to a solution of 3 g of n-propylamine and 4 g of pyridine in 20 ml of dry benzene. The reaction mixture is refluxed for 30 minutes and then processed as described in Example 3. 7.9 g (68.3%) of N-(n-propyl)-2-cyano-2-ethyl-2-phenylacetic acid amide are obtained; m.p.: 55°-56° C.

Provenance & Evidence