Diallylamine → HCID 14076562, compound

HRID 649431Notes

Reaction equation

HRID 649431 reaction equation
[C:1]([C:3]([CH2:13][CH3:14])([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:4](Cl)=[O:5])#[N:2].[CH2:15]([NH:18][CH2:19][CH:20]=[CH2:21])[CH:16]=[CH2:17]>ClCCl>[CH2:15]([N:18]([CH2:19][CH:20]=[CH2:21])[C:4](=[O:5])[C:3]([C:1]#[N:2])([CH2:13][CH3:14])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH:16]=[CH2:17]

Participants

4

Reactant 2

HCID 31279DiallylamineHCID 12625035α-Cyano-α-ethylbenzeneacetyl chloride

Product 1

HCID 14076562HCID 14076562, compoundYield 327.6%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
5 °C

Procedure

10.5 g (0.05 mole) of 2-cyano-2-ethyl-2-phenylacetyl chloride are dissolved in 50 ml of dichloromethane, the solution is cooled to 5° C., and 9.7 g (0.01 mole) of diallyl amine are added to it under maintaining the temperature of the mixture below 10° C. The reaction mixture is stirred at room temperature for 2 hours, then washed with water, dried over anhydrous magnesium sulfate, and the solvent is removed. 8.79 g (65.5%) of N,N-diallyl-2-cyano-2-ethyl-2-phenylacetic acid amide are obtained; m.p.: 33°-35° C.

Workup

  1. temperatureunder maintaining the temperature of the mixture below 10° C
  2. washwashed with water
  3. dry with materialdried over anhydrous magnesium sulfate
  4. customthe solvent is removed

Sources & evidence

ORD record
ord-000cd32cbec0472799861e192904241f
Source dataset
uspto-grants-1988_04
Patent number
US04740228

Reaction notes

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