Cyclohexylamine → HCID 14076563, compound

Participants

Reaction Steps

A solution of 9.75 g (0.05 mole) of 2-cyano-2-methyl-2-phenylacetyl chloride in 20 ml of acetone is cooled to 5° C., and a mixture of 5 g (0.05 mole) of cyclohexylamine, 5.2 g of triethyl amine and 10 ml of acetone is added to the solution under maintaining the temperature of the mixture below 10° C. The reaction mixture is poured into ice water, the separated solid is filtered off, and dried in vacuo. 12.12 g of N-cyclohexyl-2-cyano-2-methyl-2-phenylacetic acid amide are obtained; m.p.: 76°-78° C.

Provenance & Evidence