Tert-Butyl hypochlorite → HCID 86742123, compound

HRID 649512Notes

Reaction equation

HRID 649512 reaction equation
[Br:1][C:2]1[C:16]2=[C:17]3[C:5]([NH:6][CH2:7][CH:8]3[CH2:9][C@@H:10]3[C:15]2=[CH:14][C@H:13]([NH:18][C:19](=[O:25])[N:20]([CH2:23][CH3:24])[CH2:21][CH3:22])[CH2:12][N:11]3[CH3:26])=[CH:4][CH:3]=1.ClOC(C)(C)C>C(N(CC)CC)C>[Br:1][C:2]1[C:16]2=[C:17]3[C:5]([NH:6][CH:7]=[C:8]3[CH2:9][C@@H:10]3[C:15]2=[CH:14][C@H:13]([NH:18][C:19](=[O:25])[N:20]([CH2:23][CH3:24])[CH2:21][CH3:22])[CH2:12][N:11]3[CH3:26])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 521297Tert-Butyl hypochloriteHCID 86742124HCID 86742124, compound

Product 1

HCID 86742123HCID 86742123, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

This compound is prepared analogously to Example 9 by reacting 3-(12-bromo-9,10-didehydro-2,3-dihydro-6-methyl-8α-ergolinyl)-1,1-diethylurea with tert-butyl hypochlorite in the presence of triethylamine.

Workup

  1. customThis compound is prepared analogously to Example 9

Sources & evidence

ORD record
ord-5aa6c285b90f4cca972518ce7dceac13
Source dataset
uspto-grants-1988_04
Patent number
US04740509

Reaction notes

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