Nitrogen → [10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]-acetic acid methyl ester

Participants

Reaction Steps

2 g of the product of example 2 are suspended in 20 ml ethyl ether and a freshly prepared solution of diazomethane is added at 0° C. until N2 evolution ceases. The solvent is evaporated off at 10° C. and the residue re-crystallised from ethanol to yield the title compound as a (Z,E) isomer mixture: m.p.=124°-125° C.

Provenance & Evidence