Nitrogen → HCID 54079686, compound

HRID 649526Notes

Reaction equation

HRID 649526 reaction equation
[CH3:1][O:2][C:3]1[C:9]2[S:10][CH:11]=[CH:12][C:8]=2[C:7](=[CH:13][C:14]([OH:16])=[O:15])[C:6]2[CH:17]=[CH:18][CH:19]=[CH:20][C:5]=2[CH:4]=1.[N+](=[CH2:23])=[N-].N#N>C(OCC)C>[CH3:23][O:15][C:14](=[O:16])[CH:13]=[C:7]1[C:8]2[CH:12]=[CH:11][S:10][C:9]=2[C:3]([O:2][CH3:1])=[CH:4][C:5]2[CH:20]=[CH:19][CH:18]=[CH:17][C:6]1=2

Participants

5

Reactant 3

HCID 947NitrogenHCID 9550DiazomethaneHCID 3035543HCID 3035543, compound

Product 1

HCID 54079686HCID 54079686, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

2 g of the product of example 2 are suspended in 20 ml ethyl ether and a freshly prepared solution of diazomethane is added at 0° C. until N2 evolution ceases. The solvent is evaporated off at 10° C. and the residue re-crystallised from ethanol to yield the title compound as a (Z,E) isomer mixture: m.p.=124°-125° C.

Workup

  1. customThe solvent is evaporated off at 10° C.
  2. customthe residue re-crystallised from ethanol

Sources & evidence

ORD record
ord-85c7899eaa2d4c29b5e743b92005e560
Source dataset
uspto-grants-1988_04
Patent number
US04740518

Reaction notes

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