Propylamine → HCID 178457721, compound

HRID 649580Notes

Reaction equation

HRID 649580 reaction equation
[CH2:1]([NH2:4])[CH2:2][CH3:3].[CH2:5]([O:7][C:8]([N:10]1[CH2:19][CH2:18][C:17]2[N:16]=[CH:15][C:14]([C:20]([O-:22])=O)=[C:13]([OH:23])[C:12]=2[CH2:11]1)=[O:9])[CH3:6]>>[CH2:5]([O:7][C:8]([N:10]1[CH2:19][CH2:18][C:17]2[N:16]=[CH:15][C:14]([C:20](=[O:22])[NH:4][CH2:1][CH2:2][CH3:3])=[C:13]([OH:23])[C:12]=2[CH2:11]1)=[O:9])[CH3:6]

Participants

3

Reactant 2

HCID 7852PropylamineHCID 178473317HCID 178473317, compound

Product 1

HCID 178457721HCID 178457721, compound

Procedure

Reaction of N-propylamine with 6-ethoxycarbonyl-4-hydroxy-5,6,7,8-tetrahydro[1,6]naphthyridine-3-carboxylate yields 6-ethoxycarbonyl-4-hydroxy-5,6,7,8-tetrahydro-3-(N-propylcarbamoyl)[1,6]-naphthyridine, mp 199°-201°.

Sources & evidence

ORD record
ord-694348f5d3734ae5857f32deeaaff59e
Source dataset
uspto-grants-1988_04
Patent number
US04740512

Reaction notes

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