反应详情

A mixture of 2-methyl-1-undecene (35.6 g, 211 mmoles), parabromphenol (36.6 g, 211 mmoles) and Dowex 50×12 resin (100-200 mesh) previously washed with water, rinsed with acetone and oven dried for 3 hours at 80° C., is heated at 100°-110° C. for 48 hours. The mixture is then cooled to ambient temperature and chromatographed on a silica column (eluant: a mixture of dichloromethane, 40% and hexane, 60%), yielding 4-bromo-2-(1,1-dimethyldecyl)-phenol in the form of a pale yellow oil. (30.85 g, 43%).

1. washpreviously washed with water
2. washrinsed with acetone and oven
3. customdried for 3 hours at 80° C.
4. temperatureis heated at 100°-110° C. for 48 hours
5. customchromatographed on a silica column (eluant
6. additiona mixture of dichloromethane, 40% and hexane, 60%),