反应详情

Acetyl chloride (2 ml) was added to a solution of 5-hydroxy-12H-benzo[a]phenothiazine (1) (2.65 gm) in DMF (10 ml) and stirred for 30 minutes. Diethyl ether (100 ml) was added to the reaction mixture followed by ice-water (50 ml). The aqueous layer was decanted and the organic layer containing a solid was evaporated to dryness. The resulting residue was treated with acetone and filtered to afford the title compound.

1. customThe aqueous layer was decanted
2. additionthe organic layer containing a solid
3. customwas evaporated to dryness
4. additionThe resulting residue was treated with acetone
5. filtrationfiltered