Ammonia → Cyclohexylurea

HRID 649623Notes

Reaction equation

HRID 649623 reaction equation
[CH:1]1([NH2:7])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:8][C:9](N)=[O:10].N>O>[CH:1]1([NH:7][C:9]([NH2:8])=[O:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 222AmmoniaHCID 1176UreaHCID 7965Cyclohexylamine

Product 1

HCID 69684CyclohexylureaYield 90%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

495 g (5 mols) of cyclohexylamine and 390 g (6.5 mols) of urea are heated under reflux in 750 ml of water. After the splitting-off of ammonia is complete, the mixture is cooled down and the product is filtered off with suction. After washing and drying, 638 g of N-cyclohexylurea (90% of theory) are obtained.

Workup

  1. temperaturethe mixture is cooled down
  2. filtrationthe product is filtered off with suction
  3. washAfter washing
  4. customdrying

Sources & evidence

ORD record
ord-40bd685564634c348cf2844dd998dcbc
Source dataset
uspto-grants-1988_04
Patent number
US04740618

Reaction notes

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