HCID 10549647, compound → HCID 10779605, compound

HRID 649746Notes

Reaction equation

HRID 649746 reaction equation
[Cl:1][C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][N:6]2[C@@H:11]1[O:23][C@H:22]([CH2:24][O:25]C(=O)C)[C@@H:17]([O:18]C(=O)C)[C@@H:12]1[O:13]C(=O)C>N.CO>[C@@H:11]1([N:6]2[CH:5]=[N:4][C:3]3[C:7]2=[N:8][CH:9]=[N:10][C:2]=3[Cl:1])[O:23][C@H:22]([CH2:24][OH:25])[C@@H:17]([OH:18])[C@@H:12]1[OH:13]

Participants

3

Reactant 1

HCID 10549647HCID 10549647, compound

Product 1

HCID 10779605HCID 10779605, compoundYield 118.6%

Reagents, catalysts & solvents 1

HCID 21705897Ammonia methanolSolvent

Procedure

Compound 3(200 mg,0.5 mmol) was dissolved in saturated NH3/MeOH (5 mL) and stirred at room temperature for two hours. The solvent was evaporated in vacuo to obtain crude 4 (170 mg) which was used for the subsequent reaction without any further purification: UV (Me(OH)λmax 263.0 nm.

Workup

  1. customThe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-50fd73e9599347668ef1404556623365
Source dataset
uspto-grants-2001_08
Patent number
US06271212B1

Reaction notes

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