HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)piperazine → HCID 9845047, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)piperazine | HCID 75260 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 15550033 | HCID 15550033 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 9845047 | HCID 9845047 | 94% |
Reaction Steps
A suspension of 54 mg (0.17 mmol) of Compound 17, 46 mg (0.25 mmol) of 1-(4-fluorophenyl)piperazine and 57 mg (0.68 mmol) of sodium hydrogencarbonate in 3.4 ml of dioxane was refluxed for 7 hours. Post treatment and purification were conducted as in Example 9, whereby 67 mg of the title compound were obtained (yield: 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06271223B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-5a21c9471a1a40ce9578d72349958649 |
| Source note | uspto-grants-2001_08 |