Sodium Dithionite → HCID 13712507, compound

HRID 64976Notes

Reaction equation

HRID 64976 reaction equation
[OH:1][C:2]1[C:3](=[O:22])[C:4]2[CH:21]=[CH:20][CH:19]=[CH:18][C:5]=2[C:6]2[C:15]=1[S:14](=[O:17])(=[O:16])[C:13]1[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=1)[N:7]=2.S(S([O-])=O)([O-])=O.[Na+].[Na+]>O.C(OCC)(=O)C>[OH:22][C:3]1[C:2]([OH:1])=[C:15]2[C:6]([NH:7][C:8]3[C:13]([S:14]2(=[O:17])=[O:16])=[CH:12][CH:11]=[CH:10][CH:9]=3)=[C:5]2[CH:18]=[CH:19][CH:20]=[CH:21][C:4]=12

Participants

5

Reactant 2

HCID 24489Sodium DithioniteHCID 178516868HCID 178516868, compound

Product 1

HCID 13712507HCID 13712507, compoundYield 79.9%

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8857Ethyl AcetateSolvent

Procedure

To a suspension of 6-hydroxy-5H-benzo[a]phenothiazine-5-one-7,7-dioxide (430 mg) in water (10 cc) and ethyl acetate (10 ml) there was added sodium dithionite (1 g). The suspension was stirred vigorously at room temperature for 2 hours, then the insolubles were filtered and washed with water and ethyl acetate. There was obtained 346 mg of the title compound, m.p. 330° C.

Workup

  1. filtrationthe insolubles were filtered
  2. washwashed with water and ethyl acetate

Sources & evidence

ORD record
ord-3625edbaa3e8499d8511c74121f3fafb
Source dataset
uspto-grants-1986_09
Patent number
US04611056

Reaction notes

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