Potassium Fluoride → HCID 13668764, compound

HRID 64990Notes

Reaction equation

HRID 64990 reaction equation
[C:1](=[O:15])(OC(Cl)C(Cl)(Cl)Cl)[O:2][CH2:3][C:4]([CH3:7])([CH3:6])[CH3:5].[F-].[K+].[F:18]C([O-])=O>C(#N)C1C=CC=CC=1>[F:18][C:1]([O:2][CH2:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:15]

Participants

5

Reactant 3

HCID 522689Potassium FluorideHCID 14545153HCID 14545153, compound2×HCID 21917288HCID 21917288, compound

Product 1

HCID 13668764HCID 13668764, compoundYield 76%

Reagents, catalysts & solvents 1

HCID 7505BenzonitrileSolvent

Conditions

Temperature
65 °C

Procedure

In this experiment, neopentyl 1,2,2,2-tetrachloroethyl carbonate is used as the starting material. A mixture of 3.3 g (0.011 mole) of neopentyl 1,2,2,2-tetrachloroethyl carbonate, 1 g (0.017 mole) of anhydrous KF, 5 g (0.001 mole) of polyethyleneglycol monomethylether (average molecular weight 5000 Aldrich) and 10 cc of benzonitrile is heated under stirring at 65° C. (oil bath). The reaction is stopped at the end of 34 hours. By infrared and NMR analysis it is determined that the fluoroformate is obtained in a 76% yield.

Workup

  1. temperatureis heated
  2. customis stopped at the end of 34 hours
  3. customis obtained in a 76% yield

Sources & evidence

ORD record
ord-22dc0d4a30c34731a65088b3e8aeda43
Source dataset
uspto-grants-1986_09
Patent number
US04612143

Reaction notes

Loading…