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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 649938Generated: October 30, 2026

Anisole → HCID 135816418, compound

https://huagongshe.com/reaction/649938

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnisoleHCID 7519—
Reactant1-MethylpiperazineHCID 53167—
ReactantHCID 18422238HCID 18422238—
CatalystTitanium TetrachlorideHCID 24193—
ProductHCID 135816418HCID 135816418—

Reaction Steps

In the same manner as in Example 1 and using methyl 2-(2-aminoanilino)-5-methylbenzo[b]thiophene-3-carboxylate, 1-methylpiperazine, anisole and titanium tetrachloride, 2-methyl-12-(4-methylpiperazin-1-yl)-6H-[1]benzothieno[2,3-b][1,5]benzodiazepine is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06271225B1
Source datasetuspto-grants-2001_08
ORD IDord-c511c19a92774efba52d11fbf6df2109
Source noteuspto-grants-2001_08