Potassium Carbonate → HCID 10945352, compound

HRID 649995Notes

Reaction equation

HRID 649995 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([C:11]2[CH:15]=[C:14]([CH3:16])[S:13][C:12]=2Br)=[O:10])=[C:4]([OH:18])[CH:3]=1.C(=O)([O-])[O-].[K+].[K+]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]2[NH:8][C:9](=[O:10])[C:11]3[CH:15]=[C:14]([CH3:16])[S:13][C:12]=3[O:18][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 11430Potassium CarbonateHCID 11824187HCID 11824187, compound

Product 1

HCID 10945352HCID 10945352, compound

Procedure

Similar reaction is carried out using N-(4-chloro-2-hydroxyphenyl)-2-bromo-5-methyl-3-thiophenecarboxamide and potassium carbonate to give 8-chloro-2-methylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one.

Workup

  1. customSimilar reaction

Sources & evidence

ORD record
ord-55015d6afc514f59bc4979e87aa6f463
Source dataset
uspto-grants-2001_08
Patent number
US06271225B1

Reaction notes

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