Potassium Carbonate → 2,9-dimethylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one

HRID 649999Notes

Reaction equation

[OH:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[NH:9][C:10]([C:12]1[CH:16]=[C:15]([CH3:17])[S:14][C:13]=1Br)=[O:11].C(=O)([O-])[O-].[K+].[K+]>>[CH3:17][C:15]1[S:14][C:13]2[O:1][C:2]3[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=3[NH:9][C:10](=[O:11])[C:12]=2[CH:16]=1

Participants

Reactant 2

HCID 11430Potassium Carbonate

HCID 11001920N-(2-hydroxy-3-methylphenyl)-2-bromo-5-methyl-3-thiophenecarboxamide

Product 1

HCID 110321372,9-dimethylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one

Procedure

In the same manner as in Example 98 and using N-(2-hydroxy-3-methylphenyl)-2-bromo-5-methyl-3-thiophenecarboxamide and potassium carbonate, 2,9-dimethylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one is obtained.

Sources & evidence

ORD record: ord-b74bfc48a8214624b3de7490a608ec55
Source dataset: uspto-grants-2001_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06271225B1

Reaction notes

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