Butylamine → N-butyl-3-phenylpropanamide

HRID 650110Notes

Reaction equation

HRID 650110 reaction equation
[C:1]1([CH2:7][CH2:8][C:9](Cl)=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:12]([NH2:16])[CH2:13][CH2:14][CH3:15]>C(OCC)(=O)C>[CH2:12]([NH:16][C:9](=[O:10])[CH2:8][CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH2:13][CH2:14][CH3:15]

Participants

4

Reactant 2

HCID 8007ButylamineHCID 64801Benzenepropanoyl chloride

Product 1

HCID 1549146N-butyl-3-phenylpropanamide

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Following the procedure of Example 1 above and using 3-phenylpropionyl chloride and n-butylamine (and ethyl acetate in place of benzene), the title compound was prepared as a white solid, m.p. 26.7-33.1° C.

Sources & evidence

ORD record
ord-386bbf7c2ac148688bcfe9e446d12ee2
Source dataset
uspto-grants-2001_08
Patent number
US06271265B1

Reaction notes

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