1-Methylpiperazine → HCID 14327142, compound

HRID 650285Notes

Reaction equation

HRID 650285 reaction equation
[O:1]1[CH:10]2[CH:2]1[CH2:3][C:4]1[C:9]2=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:11][N:12]1[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]1>>[CH3:11][N:12]1[CH2:17][CH2:16][N:15]([CH:10]2[C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[CH2:3][CH:2]2[OH:1])[CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 92838Indene oxide

Product 1

HCID 14327142HCID 14327142, compound

Procedure

Using the procedure of Example 23, Step A, 14.57 g of 2,3-epoxy-indane and 12.4 ml of N-methyl piperazine were reacted to obtain 6.447 g of [trans (±)] 2,3-dihydro-1- (4- methyl-1-piperazinyl)-1H-inden-2-o1 melting at 132° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-46fce115f282424594cf5b4b4d132410
Source dataset
uspto-grants-2001_08
Patent number
US06271395B1

Reaction notes

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