HRID650435

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5948

Tributyltin

C12H28Sn

HCID8900

Heptane

C7H16

HCID12308

3-Bromo-1-propanol

C3H7BrO

结构：CC1(C)CC(OC(=O)CCCCCCCCC(=O)OC2CC(C)(C)N(O)C(C)(C)C2)CC(C)(C)N1O

HCID11272241

Bis-(tetramethyl hydroxypiperidinyl) sebacate

C28H52N2O6

HCID21899848

未命名化合物

PRODUCTS

生成物

结构：CC1(C)CC(OC(=O)CCCCCCCCC(=O)OC2CC(C)(C)N(OCCCO)C(C)(C)C2)CC(C)(C)N1OCCCO

HCID22507641

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID7964

Chlorobenzene

C6H5Cl

PROCEDURE

实验过程

Tributyltin hydride is added dropwise to a solution of 3-bromo-1-propanol and excess bis(1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl) sebacate in chlorobenzene. The mixture is heated to facilitate reaction. The crude reaction mixture is passed through silica gel with heptane and then heptane/ethyl acetate to afford the title compound.

WORKUP

后处理

temperatureThe mixture is heated
customreaction
customThe crude reaction mixture

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-28c02ef2eda74c36b05147765229b0e6
来源数据集: uspto-grants-2001_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06271377B1
来源说明: uspto-grants-2001_08

反应 SMILES

C([SnH](C[CH2:11][CH2:12][CH3:13])CCCC)CCC.Br[CH2:15][CH2:16][CH2:17][OH:18].[C:19]([O:43][CH:44]1[CH2:49][C:48]([CH3:51])([CH3:50])[N:47]([OH:52])[C:46]([CH3:54])([CH3:53])[CH2:45]1)(=[O:42])[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]([O:30][CH:31]1[CH2:36][C:35]([CH3:38])([CH3:37])[N:34]([OH:39])[C:33]([CH3:41])([CH3:40])[CH2:32]1)=[O:29].CCCCCCC.CCCCCCC.C(OCC)(=[O:71])C>ClC1C=CC=CC=1>[OH:18][CH2:17][CH2:16][CH2:15][O:39][N:34]1[C:33]([CH3:40])([CH3:41])[CH2:32][CH:31]([O:30][C:28](=[O:29])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][C:19]([O:43][CH:44]2[CH2:45][C:46]([CH3:54])([CH3:53])[N:47]([O:52][CH2:13][CH2:12][CH2:11][OH:71])[C:48]([CH3:51])([CH3:50])[CH2:49]2)=[O:42])[CH2:36][C:35]1([CH3:37])[CH3:38]