Methyl iodide → HCID 11426171, compound

HRID 650519Notes

Reaction equation

HRID 650519 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][N:6]=[CH:7]2.[I:12][CH3:13]>CC(C)=O>[I-:12].[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][N+:6]([CH3:13])=[CH:7]2

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 707665-Aminoisoquinoline

Product 1

HCID 11426171HCID 11426171, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 5-aminoisoquinoline (14.4 g, 100 mmol) in acetone (300 ml) was added iodomethane (14.4 ml). The solution was briefly stirred and then allowed to stand for 2 h. The yellow precipitate was then filtered, washed with acetone and dried to afford the title compound as a yellow solid (18.8 g).

Workup

  1. filtrationThe yellow precipitate was then filtered
  2. washwashed with acetone
  3. customdried

Sources & evidence

ORD record
ord-03f83c946ffc443e83813e76deb81850
Source dataset
uspto-grants-2001_08
Patent number
US06274594B1

Reaction notes

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