反应详情

In the same manner as described in Example 13 by using (1RS, 3RS)-cis-1,3-dihydroxymethyl-1,2,3,4-tetrahydro-β-carboline (0.70 g), triethylamine (0.84 ml), CS2 (0.36 ml), methyl iodide (0.37 ml) and dimethylsulfoxide (6 ml), there is prepared the title compound (369 mg, 38%) as white powder. NMR (CDCl3, δ): 2.66 (s, 3H, CSSCH3), Mass m/e: 322 (M+), 304 (M+ --H2O), 274 (M+ --CH3SH).