HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine-4-amidine hydrochloride → 4-Phenyl-2-pyridin-4-ylpyrimidine-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine-4-amidine hydrochloride | HCID 2776844 | — |
| Reactant | Ethyl-2-benzoyl-3-dimethylaminopropenoate | HCID 54499154 | — |
| Product | 4-Phenyl-2-pyridin-4-ylpyrimidine-5-carboxylic acid | HCID 21712419 | — |
Reaction Steps
In an analogous manner to that described in example 3b) starting from 2-benzoyl-3-dimethylamino-acrylic acid ethyl ester and isonicotinamidine hydrochloride, followed by saponification as described in example 3c) there was obtained 4-phenyl-2-pyridin-4-yl-pyrimidine-5-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06274588B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-9dfd58e018984f5aaf74b26b101d5d73 |
| Source note | uspto-grants-2001_08 |