HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 86741011, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Carbon Disulfide | HCID 6348 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | (1RS, 3RS)-cis-1-cyclohexyl-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline | HCID 86741012 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 86741011 | HCID 86741011 | 65.4% |
Reaction Steps
In the same manner as described in Example 13 by using (1RS, 3RS)-cis-1-cyclohexyl-3-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline (569 mg) [J.A.C.S. 102, 6976 (1980)], triethylamine (405 mg), CS2 (304 mg), methyl iodide (568 mg) and dimethylsulfoxide (5 ml), there is prepared the title compound (490 mg, 65%) as white powder. NMR (CDCl3, δ): 2.63 (s, 3H, CSSCH3), Mass m/e: 374 (M+), 326 (M+ --CH3SH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04612317 |
| Source dataset | uspto-grants-1986_09 |
| ORD ID | ord-187571651c6748f396aaf84931ea20be |
| Source note | uspto-grants-1986_09 |