Imidazole → HCID 129689385, compound

HRID 650685Notes

Reaction equation

HRID 650685 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.[H+].[B-:7]([F:11])([F:10])([F:9])[F:8]>ClCCl.C(OCC)C>[F:8][B-:7]([F:11])([F:10])[F:9].[NH+:1]1[CH:5]=[CH:4][NH:3][CH:2]=1

Participants

5

Reactant 2

HCID 795ImidazoleHCID 28118Tetrafluoroboric acid

Product 1

HCID 129689385HCID 129689385, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent2×

Procedure

To a solution of imidazole (20 mmol) in dichloromethane (30 mL) at 0° C. HBF4 (20 mmol, 3.8 g of a diethyl etherate) in dichloromethane is added dropwise. The reaction mixture is diluted with diethyl ether (100 mL) to precipitate the title compound. It is then filtered, washed with ether and recrystallized from ether.

Workup

  1. customat 0° C
  2. customto precipitate the title compound
  3. filtrationIt is then filtered
  4. washwashed with ether
  5. customrecrystallized from ether

Sources & evidence

ORD record
ord-a49c006aafe84e25ab8d16765c74025d
Source dataset
uspto-grants-2001_08
Patent number
US06274725B1

Reaction notes

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