N-(2,4-Dimethylthiophen-3-yl)-N-n-propylcarbamoyl chloride → N-(2,4-Dimethylthiophen-3-yl)-N-n-propyl-4,5-dihydro-4-(2-fluoro-phenyl)-1H-tetrazol-5-one-1-carboxamide

Participants

Reaction Steps

1.17 g (6.5 mmol) of 1,2-dihydro-1-(2-fluorophenyl)-5H-tetrazol-5-one, 1.5 g (6.5 mmol) of N-(2,4-dimethyl-thiophen-3-yl)-N-n-propylcarbamoyl chloride and 1.19 g (9.7 mmol) of 4-dimethylaminopyridine were reacted by the method of the process described in Example 1. Yield 1.9 g.

Provenance & Evidence