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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 650875Erstellt: 25. Oktober 2026

N-Propyl-N-(tetrahydrofuran-3-yl)carbamoyl chloride → N-Propyl-N-(tetrahydrofuran-3-yl)-4,5-dihydro-4-(2-fluorophenyl)-1H-tetrazol-5-one-1-carboxamide

https://huagongshe.com/reaction/650875

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktN-Propyl-N-(tetrahydrofuran-3-yl)carbamoyl chlorideHCID 21709911—
EduktHCID 178518973HCID 178518973—
Katalysator4-(Dimethylamino)pyridineHCID 14284—
ProduktN-Propyl-N-(tetrahydrofuran-3-yl)-4,5-dihydro-4-(2-fluorophenyl)-1H-tetrazol-5-one-1-carboxamideHCID 21709940—

Reaktionsschritte

1.4 g (7.8 mmol) of 1,2-dihydro-1-(2-fluorophenyl)-5H-tetrazol-5-one, 1.5 g (7.8 mmol) of N-propyl-N-(tetrahydro-furan-3-yl)carbamoyl chloride and 1.29 g (10 mmol) of 4-dimethylaminopyridine were reacted by the method of the process described in Example 1. Yield 2.1 g.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06277790B1
Quelldatensatzuspto-grants-2001_08
ORD IDord-92c9e84815214661af094841c5484a7c
Quellennotizuspto-grants-2001_08