Lithium Hydroxide → HCID 15840184, compound

HRID 650896Notes

Reaction equation

HRID 650896 reaction equation
C([O:3][C:4]([C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13](=[O:37])[NH:14][CH2:15][C:16]2[CH:20]=[CH:19][N:18]([C:21]3[CH:30]=[C:29]4[C:24]([NH:25][C:26](=[O:32])[C:27](=[O:31])[NH:28]4)=[CH:23][C:22]=3[C:33]([F:36])([F:35])[F:34])[CH:17]=2)=[CH:8][CH:7]=1)=[O:5])C.[OH-].[Li+]>O>[C:4]([C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13](=[O:37])[NH:14][CH2:15][C:16]2[CH:20]=[CH:19][N:18]([C:21]3[CH:30]=[C:29]4[C:24]([NH:25][C:26](=[O:32])[C:27](=[O:31])[NH:28]4)=[CH:23][C:22]=3[C:33]([F:36])([F:35])[F:34])[CH:17]=2)=[CH:8][CH:7]=1)([OH:5])=[O:3]

Participants

4

Reactant 2

HCID 3939Lithium HydroxideHCID 15840183HCID 15840183, compound

Product 1

HCID 15840184HCID 15840184, compoundYield 74%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1.6 g (3.1 mmol) of the compound from Example 1 and 0.3 g (12.4 mmol) of lithium hydroxide were stirred in 40 ml of water at room temperature for 2 h. The mixture was then filtered, and the filtrate was neutralized with 1 M hydrochloric acid. The resulting precipitate was filtered off with suction. 1.1 g (74%) of the product were obtained.

Workup

  1. filtrationThe mixture was then filtered
  2. filtrationThe resulting precipitate was filtered off with suction

Sources & evidence

ORD record
ord-49bd5d1a0d3c498d80aecc01bddb5389
Source dataset
uspto-grants-2001_08
Patent number
US06277850B1

Reaction notes

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