Lithium Hydroxide → HCID 15840189, compound

HRID 650899Notes

Reaction equation

C([O:3][C:4]([C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13](=[O:40])[NH:14][CH2:15][C:16]2[CH:20]=[CH:19][N:18]([C:21]3[CH:30]=[C:29]4[C:24]([NH:25][C:26](=[O:35])[C:27](=[O:34])[N:28]4[CH2:31][CH2:32][OH:33])=[CH:23][C:22]=3[C:36]([F:39])([F:38])[F:37])[CH:17]=2)=[CH:8][CH:7]=1)=[O:5])C.[OH-].[Li+]>>[C:4]([C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13](=[O:40])[NH:14][CH2:15][C:16]2[CH:20]=[CH:19][N:18]([C:21]3[CH:30]=[C:29]4[C:24]([NH:25][C:26](=[O:35])[C:27](=[O:34])[N:28]4[CH2:31][CH2:32][OH:33])=[CH:23][C:22]=3[C:36]([F:39])([F:37])[F:38])[CH:17]=2)=[CH:8][CH:7]=1)([OH:5])=[O:3]

Participants

Reactant 2

HCID 3939Lithium Hydroxide

HCID 15840188HCID 15840188, compound

Product 1

HCID 15840189HCID 15840189, compoundYield 94.1%

Procedure

0.66 g (1.2 mmol) of the compound from Example 7 and 0.14 g (8.6 mmol) of lithium hydroxide were reacted via the method of Example 4, resulting in 0.6 g (89%) of the product.

Sources & evidence

ORD record: ord-1aed157d12434851ba8e12648d4b12b9
Source dataset: uspto-grants-2001_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06277850B1

Reaction notes

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