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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 650930Generated: October 29, 2026

4-(4-Oxazol-2-ylphenyl)piperazine → 2-[3-(2-Aminoethyl)-1h-indol-5-yloxy]-1-[4-(4-oxazol-2-ylphenyl)piperazin-1-yl]ethanone fumarate

https://huagongshe.com/reaction/650930

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Oxazol-2-ylphenyl)piperazineHCID 18504836—
Reactant1-[4-(5-Phenyl-[1,3,4]oxadiazol-2-yl)phenyl]piperazineHCID 18504839—
ReactantSerBOCHCID 57270561—
Product2-[3-(2-Aminoethyl)-1h-indol-5-yloxy]-1-[4-(4-oxazol-2-ylphenyl)piperazin-1-yl]ethanone fumarateHCID 18504845—

Reaction Steps

Compound 6 is prepared from intermediate 6A (54 mg; 0.16 mmol) and SerBOC acid (53 mg; 0.16 mmol) according to the procedure described for the preparation of Example 1 from 1C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06277853B1
Source datasetuspto-grants-2001_08
ORD IDord-a7978e6e43a84096942b10e4b385d0df
Source noteuspto-grants-2001_08