Phenacyl bromide → HCID 18367847, compound

HRID 651031Notes

Reaction equation

[CH2:1]([O:3][C:4]([NH:6][C:7]1[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:8]=1[C:9]#[N:10])=[O:5])[CH3:2].Br[CH2:17][C:18]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:19]>>[NH2:10][C:9]1[C:8]2[C:7](=[CH:14][C:13]([F:15])=[CH:12][CH:11]=2)[N:6]([C:4]([O:3][CH2:1][CH3:2])=[O:5])[C:17]=1[C:18](=[O:19])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

Reactant 2

HCID 6259Phenacyl bromide

HCID 18367852HCID 18367852, compound

Product 1

HCID 18367847HCID 18367847, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 1 from 2-[(ethoxycarbonyl)amino]-4fluorobenzonitrile (step 1) and 2-bromoacetophenone.

Sources & evidence

ORD record: ord-9d6953ab5d1747918ea3f5ba852856fb
Source dataset: uspto-grants-2001_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06277878B1

Reaction notes

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