HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 651127Generated: October 30, 2026
HCID 468478, compound → HCID 69688732, compound
https://huagongshe.com/reaction/651127
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 468478 | HCID 468478 | — |
| Reactant | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Product | HCID 69688732 | HCID 69688732 | — |
Reaction Steps
(S)-[1-Benzyl-2-oxo-2-(3-oxo-pyrrolidin-1-yl)-ethyl]-carbamic acid tert-butyl ester (552 mg, 1.7 mmol) was dissolved in 4M HCl-dioxane (6.2 mL) at 0° C. The mixture was stirred at 25° C. for 1 hour, concentrated and the residue triturated with ether to give alight brown solid. Yield, 482 mg, 108%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06277877B1 |
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| Source dataset | uspto-grants-2001_08 |
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| ORD ID | ord-63348ef3142a4c519944e519219e2e3d |
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| Source note | uspto-grants-2001_08 |
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