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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 651127Generated: October 30, 2026

HCID 468478, compound → HCID 69688732, compound

https://huagongshe.com/reaction/651127

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 468478HCID 468478—
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
ProductHCID 69688732HCID 69688732—

Reaction Conditions

Temperature25 °C

Reaction Steps

(S)-[1-Benzyl-2-oxo-2-(3-oxo-pyrrolidin-1-yl)-ethyl]-carbamic acid tert-butyl ester (552 mg, 1.7 mmol) was dissolved in 4M HCl-dioxane (6.2 mL) at 0° C. The mixture was stirred at 25° C. for 1 hour, concentrated and the residue triturated with ether to give alight brown solid. Yield, 482 mg, 108%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06277877B1
Source datasetuspto-grants-2001_08
ORD IDord-63348ef3142a4c519944e519219e2e3d
Source noteuspto-grants-2001_08