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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 651189Generated: October 30, 2026

1,4-Dioxane hydrochloride → HCID 69687670, compound

https://huagongshe.com/reaction/651189

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
ReactantHCID 69687358HCID 69687358—
ProductHCID 69687670HCID 69687670—

Reaction Conditions

Temperature25 °C

Reaction Steps

[(1S)-Benzyl-2-(3-hydroxy-azetidin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester (515 mg, 1.6 mmol) was dissolved in cold 4N HCl-dioxane, the mixture stirred 2 h at 25° C., concentrated, and the residue with ether giving a colorless solid (415 mg, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06277877B1
Source datasetuspto-grants-2001_08
ORD IDord-360dee2c65324de1bbc7844bf421a0ca
Source noteuspto-grants-2001_08