HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → N-(3-methoxyphenyl)-2-phenylquinazolin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Chloro-2-phenylquinazoline | HCID 80977 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | N-(3-methoxyphenyl)-2-phenylquinazolin-4-amine | HCID 4841865 | — |
Reaction Steps
4-Chloro-2-phenylquinazoline, 2 equivalents, 3-methoxyanilinyl, 2 equivalents, and potassium carbonate, 2 equivalents, were dissolved in 10 mL isopropanol and refluxed for 2 hours. The precipitated product formed was filtered and washed with water. Recrystallization from methanol provided the product as a white solid that was found to be homogenous by thin layer chromatography (TLC) and confirmed by EIMS.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06277989B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-dc33460735504293812160d126e6febd |
| Source note | uspto-grants-2001_08 |