Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2-Methylacetanilide | HCID 12107 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22465461 | HCID 22465461 | — |
Reaction Steps
N-phenylpropionamide(149.2 g, 1.0 mol) and pyridine(261.0 g, 3.3 mol) were dissolved in dichloromethane(300 g), and the mixture was cooled to 0° C. Phosphorus oxychloride(168.7 g, 1.1 mol) was added dropwise thereto for 2 hours, and then the mixture was stirred at room temperature (20° C.) for 2 hours to produce N-phenylpropionimidoylchloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06277995B1 |
|---|
| Source dataset | uspto-grants-2001_08 |
|---|
| ORD ID | ord-356303691e63401ea120afc8bd3fb6eb |
|---|
| Source note | uspto-grants-2001_08 |
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