反应详情

温度

80 °C

A mixture of 4-cyanobenzyl azide (0.8 g) and 2-chloroacrylonitrile (0.88 9) in water (5 ml) is stirred at about 80° C. for 20 hours. Excess 2-chloroacrylonitrile is distilled off in vacuo, the mixture is cooled to room temperature and the precipitated product is isolated by filtration and washed with water. The product (yield 0.92 g; 88% of theory) of m.p. 93.5-94° C. (recrystallization from ethyl acetate/toluene) is obtained after drying.

1. distillationExcess 2-chloroacrylonitrile is distilled off in vacuo
2. temperaturethe mixture is cooled to room temperature
3. customthe precipitated product is isolated by filtration
4. washwashed with water
5. customThe product (yield 0.92 g; 88% of theory) of m.p. 93.5-94° C. (recrystallization from ethyl acetate/toluene)
6. customis obtained
7. customafter drying