Potassium Carbonate → Ethyl 8-cyano-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate

Participants

Reaction Steps

A mixture of the crude product from step f, 27,6 g of K2CO3, and 80 ml of dimethylformamide are stirred at room temperature for 16 hours. The reaction mixture is poured on 750 ml ice/water and the precipitate is filtered off with suction, washed with 80 ml of cold methanol and dried.

Provenance & Evidence